Laboratory Publications

Please find a list of selected laboratory publications (PDF) as follows:

	Ahmadpour F., Ghirlando R., De Jong A.T., Gloyd M., Shin J.A., Guarné A. Crystal structure of the minimalist Max-E47 protein chimera. PLoS ONE (2012), 7(2):e32136.
	Matthews L.A., Jones D.R., Prasad A.A., Duncker B.P., Guarné A. Saccharomyces cerevisiae Dbf4 has a unique fold necessary for the interaction with the Rad53 kinase. J. Biol. Chem. (2012) 287(4):2378-87.
	Gloyd M., Ghirlando R., Guarné A. The role of MukE in assembling a functional MukBEF complex. J. Mol. Biol. (2011), 412(4):578-90.
	Pillon M.C., Miller J.H., GUarné A. The endonuclease domain of MutL interacts with the beta sliding clamp. DNA Repair (2011), 10(1):87-93.
	Chung YS., Guarné A. Crystallization and preliminary X-ray diffraction analysis of SeqA bound to a pair of hemimethylated GATC sites. Acta Cryst.(2008) F64:567-71.
	Li D.H.S., Chung YS., Gloyd M., Joseph E., Ghirlando R., Wright G.D., Cheng Y-Q., Maurizi M.R., Guarné A., Ortega J. Acyldepsipeptide antibiotics induces the formation of a structured axial channel in ClpP: a model for the ClpX/ClpA bound state of ClpP. Chem. & Biol. (2010), 17(9):959-69.
	Pillon M.C., Lorenowicz J.J., Uckelmann M., Klocko A.D., Mitchell R.R., Chung YS., Modrich P., Walker G.C., Simmons L.A., Friedhoff P., Guarné A. Structure of the endonuclease domain of MutL: unlicensed to cut. Mol. Cell. (2010), 39(1):145-51.
	Matthews L.A., Duong A., Prasad A.A., Duncker B.P., Guarné A. Crystallization and preliminary X-ray diffraction analysis of motif N from Saccharomyces cerevisiae Dbf4. (2009) Acta Cryst. F65:890-4.
	Chung YS., Brendler T., Austin S., Guarné A. Structural insights into the cooperative binding of SeqA to a tandem GATC repeat. Nucleic Acids Research (2009), 37(10):3143-52.
	Chung YS., Guarné A. Crystallization and preliminary X-ray diffraction analysis of SeqA bound to a pair of hemimethylated GATC sites. Acta Cryst. (2008), F64:567-71.
	Gloyd M., Ghirlando R., Matthews L.A., Guarné A. MukE and MukF form two distinct high-affinity complexes. J. Biol. Chem. (2007), 282(19):14373-8.
	Guarne A., Brendler T., Zhao Q., Ghirlando R., Austin S., Yang W. Crystal Structure of a SeqA-N Filament: implications for DNA replication and chromosome organization. (2005) The EMBO Journal. 1-10.
	Guarne A., Ramon-Maiques S., Wolff E. M., Ghirlando R., Hu X., Miller J., Yang W. Structure of the MutL C-terminal domain: a model of intact MutL and it's role in mismatch repair. (2004) The EMBO Journal. 23:4134-4145.
	Carpena X., Guarne A., Ferrer J.C., Alzari P. M., Fita I., Loewen P. Crystallization and preliminary X-ray analysis of the hydroxidase I C-terminal domain from Escherichia coli. (2002) Acta Cryst. D58:853-855.
	Guarne A., Zhao Q., Ghirlando R., Yang W.Insights into negative modulation of E.coli replication initiation from the structure of SeqA-hemimethylated DNA complex. (2002) Nature Structural Biology. 19, 11: 839-843.
	Guarne A., Junop M. S., Yang W. Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase. (2001) The EMBO Journal. 20, 19: 5521-5531.
	Junop M. S., Modesti M., Guarne A., Ghirlando R., Gellert M., Yang W. Crystal structure of the Xrcc4 DNA repair protein and implications for end joining. (2000) The EMBO Journal. 19, 22: 5962-5970.
	Guarne A., Hampoelz B., Glaser W., Carpena X., Tormo J., Fita I., Skern T. Structural and Biochemical Features Distinguish the Foot-and-Mouth Diease Virus Leader Proteinase from Other Papain-like Enzymes. (2000) J. Mol. Biol. 302:1227-1240.
	Seipelt J., Guarne A., Bergmann E., James M., Sommergruber W., Fita I., Skern T. The structures of picornaviral proteinases. (1999) Virus Research. 62:159-168.
	Skern T., Fita I., Guarne A. A Structural model of picornavirus leader proteinases based on papain and bleomycin hydrolase. (1998) Journal of General Virology. 79: 301-307.
	Guarne A., Tormo J., Kirchweger R., Pfistermueller D., Fita I., Skern T. Structure of the foot-and-mouth disease virus leader protease: a papain-like fold adapted for self-processing and elF4G recognition. (1998) The EMBO Journal. 17, 24:7469-7479.
	Guarne A, Kirchweger R, Verdaguer N, Liebig HD, Blaas D, Skern T, Fita I. Crystallization and preliminary X-ray diffraction studies of the Lb proteinase from foot-and-mouth disease virus. Protein Sci. (1996), 5(9):1931-3.
	Guarne A, Bravo J, Calvo J, Lozano F, Vives J, Fita I.Conformation of the hypervariable region L3 without the key proline residue. (1996) Protein Science.5(1):167-9.